{"id":32868,"date":"2023-04-02T12:04:28","date_gmt":"2023-04-02T09:04:28","guid":{"rendered":"https:\/\/labcare.gr\/?p=32868"},"modified":"2023-04-18T23:54:22","modified_gmt":"2023-04-18T20:54:22","slug":"transaminases-sgot_ast-sgpt_alt","status":"publish","type":"post","link":"https:\/\/labcare.gr\/en\/transaminases-sgot_ast-sgpt_alt\/","title":{"rendered":"Transaminases (SGOT &#8211; AST &#038; SGPT &#8211; ALT)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<strong>About the test<\/strong><\/p>\n<p>Transaminases are hepatic enzymes whose value is elevated mainly in hepatic disease.<\/p>\n<p>There are two kinds of transaminases:<\/p>\n<p>1. The serum glutamic oxaloacetic transaminase or aspartate \u00a0aminotransferase(<strong>SGOT \/ AST<\/strong>).<\/p>\n<p>2. The serum glutamate pyruvate transaminase or alanine aminotransferase (<strong>SGPT \/ ALT<\/strong>).<\/p>\n<p><strong>SGOT\/AST<\/strong><\/p>\n<p>SGOT is found in the liver, the heart, the muscles and the kidneys. Its screening results in measurement of its quantity that has been released from injured tissues.<\/p>\n<p><strong>SGPT\/ALT<\/strong><\/p>\n<p>SGPT is found mainly in the liver and that\u2019s why it constitutes a more specific index of hepatocyte impairment related to SGOT.<\/p>\n<p><strong>Sample<\/strong><\/p>\n<p>Venous blood<\/p>\n<p><strong>Preparation<\/strong><\/p>\n<p>None required. Water is allowed.<\/p>\n<p><strong>Procedure<\/strong><\/p>\n<p>Venipuncture<\/p>\n<p><strong>Increased values<\/strong><\/p>\n<ul>\n<li>Viral hepatitides<\/li>\n<li>Alcoholic disease of the liver<\/li>\n<li>Nonalcoholic fatty liver disease<\/li>\n<li>Autoimmune hepatitis<\/li>\n<li>Liver cancer<\/li>\n<li>Myocardial infarction<\/li>\n<li>Bile duct obstruction<\/li>\n<li>Drugs (paracetamol, antiepileptics, antibiotics, salicylates, non-steroidal anti-inflammatory drugs, heparin, iron)<\/li>\n<li>Infectious mononucleosis<\/li>\n<li>Toxic substances<\/li>\n<li>Budd Chiari syndrome<\/li>\n<li>Hemochromatosis<\/li>\n<li>Addison\u2019s disease<\/li>\n<li>Hypothyroidism<\/li>\n<li>Anorexia nervosa<\/li>\n<\/ul>\n<p><strong>Decreased values<\/strong><\/p>\n<ul>\n<li>Pregnancy<\/li>\n<li>Uremia<\/li>\n<li>Drugs (metronidazole)<\/li>\n<li>Diabetic ketoacidosis<\/li>\n<\/ul>\n<p><strong>Additional information<\/strong><\/p>\n<p>The degree of transaminases\u2019 elevation as well as the analogy SGOT\/SGPT constitutes an important diagnostic tools for medical doctors. For example, a small transaminase elevation is usually indicative of obstruction, whereas a bigger elevation suggests hepatitis.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Transaminases are hepatic enzymes whose value is elevated mainly in hepatic disease. There are two kinds of transaminases<\/p>\n","protected":false},"author":1,"featured_media":33186,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[55],"tags":[],"class_list":["post-32868","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-list-of-exams"],"_links":{"self":[{"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/posts\/32868","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/comments?post=32868"}],"version-history":[{"count":3,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/posts\/32868\/revisions"}],"predecessor-version":[{"id":33508,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/posts\/32868\/revisions\/33508"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/media\/33186"}],"wp:attachment":[{"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/media?parent=32868"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/categories?post=32868"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labcare.gr\/en\/wp-json\/wp\/v2\/tags?post=32868"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}